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Cat. No. Product Name Species Expression System
TMPJ-00418 TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)

Decoy Receptor 1,Antagonist Decoy Receptor...

Human HEK293 Cells
Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.
TMPY-04722 DcR1/TRAILR3 Protein, Human, Recombinant (His)

TRAILR3,TRID,DCR1,TRAIL-R3,CD263,DCR1-TNFR...

Human HEK293 Cells
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC.

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TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00418
Species: Human
Expression System: HEK293 Cells
DcR1/TRAILR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04722
Species: Human
Expression System: HEK293 Cells
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